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Social isolation is an epidemic in the United States, affecting two-thirds of older adults and three-quarters of young people (as reported during COVID). Social isolation is linked to depression, poor sleep, and impaired immunity. It increases the risks of dementia by 50 percent, stroke by 32 percent, and coronary heart disease by 29 percent, and significantly increases the risk of premature death from all causes.

This report summarizes key issues relevant to understanding complex care and offers resources and case studies for funders interested in entering the field or deepening their existing work. It also profiles funding opportunities, explores existing models, and shares philanthropic lessons learned.